Manage several third-party anti-virus vendor technologies across both Windows and Mac platforms with the use of the IBM® Tivoli® Endpoint Manager Client Manager for Endpoint Protection Fixlet site.
| Vendor | Product | Supported Versions | Supported OS |
| Computer Associates | eTrust (CA Antivirus) | eTrust AntiVirus 6, 7.1, 8, CA Antivirus R12 (Audit only*) (x86, x64) | Windows NT 4 SP6+, Windows 2000, Windows XP Professional, Windows Server 2003, Windows Vista, Windows Server 2008, Windows Server 2008 R2, Windows 7 |
| CA Antivirus for Mac | 8.x | Mac OS X 10.2+ | |
| IBM | IBM Proventia Desktop | 8.0, 9.0, 10.0 (Audit only*) | Windows 2000 SP3+, Windows XP Professional SP 1+, Windows Vista Enterprise, Windows 7 SP1 |
| McAfee | VirusScan | 4.03 – 8.x | Windows 98, Me, Windows NT 4 SP6+, Windows XP, Windows 2000 SP4+, Windows Server 2003 SP1+, Windows Vista, Windows 7 |
| VirusScan for Mac | 8.x | Mac OS X 10.4.6 or later | |
| NetShield | 4.5 + | Win NT/2000 | |
| McAfee GroupShield for Microsoft Exchange / McAfee Security for Microsoft Exchange | McAfee Group Shield 7.0, McAfee Security 7.6 | Windows 2000 SP1+, Windows Server 2003, Windows Server 2008, Windows Server 2008 R2 | |
| AVERT Stinger | N/A | Windows 2000, Windows XP Professional, Windows Server 2003, Windows Vista, Windows Server 2008, Windows Server 2008 R2, Windows 7 | |
| Microsoft | Windows Defender | N/A | Windows XP, Windows Vista, Windows Server 2003, Windows 7, Windows Server 2008 |
| Forefront Client Security/ Forefront Endpoint Protection 2010 | N/A | Windows XP, Windows Server 2003, Windows Vista, Windows Server 2008, Windows Server 2008 R2, Windows 7 | |
| Symantec | Anti-Virus Corporate Edition | 7.6, 8, 9, 10, 10.1, 10.2 | Windows 95, Windows 98, Windows Me, Windows NT 4 SP6,Windows 2000, Windows XP Professional, Windows Server 2003 |
| Anti-Virus Corporate Edition x64 | All versions | Windows XP 64-Bit Version 2003, Windows Server 2003 64-Bit, Windows Vista, Windows Server 2008 | |
| Anti-Virus for Mac | 10.2 | Mac OS X 10.3.9+ | |
| Endpoint Protection | 11, 12.1 | Windows 2000, Windows 2008, Windows Vista, Windows 2000 SP3+, Windows Server 2003, Windows Server 2008, Windows 7 | |
| Endpoint Protection for Mac | 12 | Mac OS X 10.5+ | |
| Sophos | Antivirus / Endpoint Security | Antivirus 3.x, 4.1x, 4.6x, 6.x, 7.x, 9.x | Windows 95 OSR2, Windows 98 SE, Windows NT 4 SP6+, Windows XP SP1+, Windows Vista, Windows Server 2003, Windows Server 2003 R2, Windows Server 2008, Windows Server 2008 R2, Windows 7 |
| Antivirus for Mac | 7.x | Mac OS X 10.4+ | |
| Trend Micro | OfficeScan | 7, 8, 10, 10.5, 10.6 | Windows 2000, Windows XP Pro SP2+, Windows XP Home SP3+, Windows Server 2003 SP2+ Windows Server 2003 R2 SP2+, Windows Vista SP1+, Windows Server 2008 SP1+, Windows 7 |
| ServerProtect | 5.5, 5.8 | Windows 2000 SP4+, Windows Server 2003 SP1+, Windows Server 2008 | |
| Trend Micro Security for Mac | 1.5 | Mac OS X 10.+ |